恒河猴白介素8 (IL-8) (Rhesus macaque)
Interleukin-8 (C-X-C motif chemokine 8) is coded by the interleukin 8 gene on the chromosome 5 in Rhesus macaque (Macaca mulatta), which is not only 94% identical to human IL-8 but also structurally and functionally similar with the human equivalent. Provide a valuable resource for a primate model of inflammation.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Approximately 9.14kD containing 79 amino acid residues.
Less than 1 EU/μg of IL-8 as determined by LAL method.
This material is offered by Cyagen Biosciences for research, laboratory or further evaluation purposes. FOR RESEARCH USE ONLY. NOT INTENDED FOR ANY ANIMAL OR HUMAN THERAP EUTIC OR DIAGNOSTIC USE.
The biologically active determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 0.5-5.0 ng/mL.
Sterile filtered white lyophilized (freeze-dried) powder.
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> 95% by SDS-PAGE and HPLC analyses.