产品描述：

Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems.

表达系统 :

Escherichia coli

溶解方法:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile 4 mM HCl to a concentration of 0.1 -1.5 mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C.Further dilutions should be made in appropriately buffered solutions.

产品组成:

Lyophilized from a 0.2 μm filtered concentrated solution in 30% Acetonitrile and 0.1% TFA.

存储条件:

This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.

分子量:

Approximately 27.1 kDa,a disulfide-linked homodimeric protein containing two 120 amino acids.

内毒素:

Less than 1 EU/μg of rHuGDF-5/BMP-14 as determined by LAL method.

产品用途:

This material is offered by Cyagen Biosciences for research, laboratory or further evaluation purposes. FOR RESEARCH USE ONLY. NOT INTENDED FOR ANY ANIMAL OR HUMAN THERAP EUTIC OR DIAGNOSTIC USE.

生物学活性:

产品形态:

Sterile filtered white lyophilized (freeze-dried) powder.

氨基酸序列:

产品纯度:
> 95% by SDS-PAGE and HPLC analyses.